Studied since 2007 · Ohsawa, Nature Medicine
Up to ~9,000 PPB · manufacturer's data
Verifiable with the DPD test · kit ~20 €
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Science
What the literature says.
Molecular hydrogen (H₂) has been studied since 2007 — the seminal publication by Ohsawa et al. in Nature Medicine.
H₂ acts as a selective antioxidant: it targets the hydroxyl radical (OH·) and peroxynitrite (ONOO-), without neutralizing species useful for cell signaling.
Since then, several hundred studies have been published in peer-reviewed journals: sport and recovery, oxidative stress, metabolism, fatigue, and mood.
7 reference studies are summarized on the studies page — cited as research, never as proof of effect.
Key Figures
Literature in 4 figures.
1,000+
scientific publications on H₂
2007
first publication, Ohsawa, Nature Medicine
7
synthesized reference studies
9,000
PPB · manufacturer's data, verifiable by DPD test
2007 → Present
Research, year by year.
-
2007 · Ohsawa et al.
Nature Medicine. Landmark publication: H₂ identified as a selective antioxidant targeting OH· and ONOO- (preclinical models).
-
2008 · Kajiyama et al.
Nutrition Research. Controlled trial in adults with impaired glucose metabolism: decrease in oxidative stress markers observed vs. placebo.
-
2012 · Aoki et al.
Medical Gas Research. Elite footballers, n=10, crossover study vs placebo: decrease in blood lactate observed during exercise.
-
2017 · Mizuno et al.
Medical Gas Research. Pilot study in healthy adults: fatigue and mood scores followed over 4 weeks.
-
Today
Hundreds of PubMed-indexed publications, literature reviews (LeBaron 2019, Ostojic). An active field of research — not proof of effect.
Fields of Study
What is documented.
Sport & Recovery
Aoki 2012 (Medical Gas Research, footballers): decrease in blood lactate observed during exercise. Ostojic: sport and recovery.
Oxidative stress
Ohsawa 2007 (Nature Medicine): selective antioxidant targeting OH· and ONOO-, without affecting useful ROS.
Fatigue & Mood
Mizuno 2017 (pilot study, healthy adults): fatigue and mood scores. LeBaron: literature reviews.
Metabolism
Kajiyama 2008 (Nutrition Research, adults with impaired glucose metabolism): study observed a decrease in oxidative stress markers.
Scientific Honesty
"Hydrogen is not a drug. No curative effect has been demonstrated. But several hundred publications converge on a modulating effect on oxidative stress.
We summarize this literature — without distorting it."
HYDROGENYX Team · French brand
Go further
Dig, check, compare.
The 7 Studies
Summary sheets: review, sample, protocol, observed result. No embellishment.
Explore →
The DPD protocol
5 steps, 8 minutes: measure the concentration of dissolved H₂ in your glass yourself.
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HYDROGENYX Flask · €239
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The HYDROGENYX Flask is a water preparation device, not a medical device. It does not prevent, treat, or cure any disease.